Int J Curr Res Aca Rev 4(11):1824 http://www.ijcrar.com/abstractview.php?ID=228&vol=4-11-2016&SNo=3, Kim TH, Lee DH, Lee SH, Kim JM, Kim CW, Bin SI (2008) Arthroscopic treatment of mucoid hypertrophy of the anterior cruciate ligament. Posterior pain disappeared in 27 cases (93%), on average 3.7 weeks after the procedure. maude adverse event report: genzyme biosurgery (ridgefield) synvisc one intra-articular hyaluronic acid Knee Surg Sports Traumatol Arthrosc. This was lowest in the study of Cha et al. Epub 2008 Dec 17. 2013 Oct;99(6):693-7. doi: 10.1016/j.otsr.2013.04.010. When refering to evidence in academic writing, you should always try to reference the primary (original) source. This bicentric, retrospective cohort study with an average follow-up of 6years involved 27 patients (29 knees) presenting with symptomatic ACL mucoid degeneration validated by magnetic resonance imaging (MRI). eCollection 2022 May-Jun. Treatment of ACL mucoid degeneration by arthroscopic resection is effective for posterior pain and flexion limitation. Before This is a rare pathological condition, in which, there is increased signal from within the ligament. An official website of the United States government. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2022 Apr 11;31:67-71. doi: 10.1016/j.jor.2022.04.004. What causes mucoid degeneration of ACL? Anterior cruciate ligament mucoid degeneration: Selecting the best -, Bergin D, Morrison WB, Carrino JA, Nallamshetty SN, Bartolozzi AR. Demographic, radiological, and histological findings, type of surgery, and clinical pre- and postoperative data were analyzed. Management of mucoid degeneration of the anterior cruciate ligament: a systematic review. There was a high rate of association between degenerative lesions and MDACL, ranging from 39 to 96%. PMC Its signal is increased on all sequences. Careers. 2004;182(5):12831287. Symptomatic ACL mucoid degeneration in middle-age athletes. Coronal proton density-weighted magnetic resonance, Coronal proton density-weighted magnetic resonance imaging shows a thickening of the anterior cruciate, Sagittal proton density-weighted magnetic resonance, Sagittal proton density-weighted magnetic resonance image shows ill-defined anterior cruciate ligament with increased, Coronal T2 weighted fat suppressed fast spin echo image showed complex anterior cruciate, Pre-debridement arthroscopic view showing yellowish. Postoperative Lachman test was positive in 40% of patients, and 6% of patients had symptomatic instability. Clinical Outcomes, Return to Sports, and Patient Satisfaction After Anterior Cruciate Ligament Reconstruction in Young and Middle-Aged Patients in an Asian Population-A 2-Year Follow-up Study. Lintz F, Pujol N, Dejour D, Boisrenoult P, Beaufils P. Orthop Traumatol Surg Res. PDF Anterior Cruciate Ligament Ganglion Cyst and Mucoid Degeneration: A Review PMC Radiology. J Chin Med Assoc. A historical cohort of patients who underwent arthroscopic total or partial excision of the anterior cruciate ligament due to mucoid degeneration between 2011 and 2014 were reviewed. HHS Vulnerability Disclosure, Help ACL mucoid degeneration is an uncommon pathological condition; the pathogenesis, prevalence, and association with other intra-articular knee structural damage are still poorly understood. J Knee Surg. Mucoid degeneration of the anterior cruciate ligament: MRI, clinical, intraoperative, and histological findings. Finally, partial meniscectomy was commonly performed simultaneously with ACL debridement in all studies, which arguably could be the reason for the postoperative improvement. 2004 Feb;20(2):141-6. doi: 10.1016/j.arthro.2003.11.030. What Is Mucoid Degeneration of the ACL? Morice et al. Disclaimer. . Mucoid degeneration of the ACL is a rare cause of knee pain.1-8) This lesion of the ACL was first reported by Kumar et al.3) in 1999. Epidemiology The likelihood of mucoid change within ligaments and tendons increases with age 1. Bookshelf CONFLICT OF INTEREST: No potential conflict of interest relevant to this article was reported. California Privacy Statement, Anterior cruciate ligament mucoid degeneration - Radiopaedia Possible etiologies include: It is postulated that mucoid degeneration may be a predisposing factor in the formation of ACL ganglion cysts. An official website of the United States government. 2011 Aug 1;19(8):1326-33. Bergin D, Morrison WB, Carrino JA, Nallamshetty SN, Bartolozzi AR. (PDF) Assessment of imaging, pathoanatomy and - Academia.edu On MRI, the ligament is thickened and ill-defined with a "celery stalk" appearance. 8600 Rockville Pike Read More Created for people with ongoing healthcare needs but benefits everyone. Ligaments and tendons are accumulated by mucoid change might display a thickened and/or hypertrophied appearance, with an increase in signal intensity. 2011 Aug;19(8):1326-33. doi: 10.1007/s00167-011-1433-0. IV (retrospective cohort study). Nowadays, orthobiologics such as platelet-rich plasma (PRP) are increasingly used in ligament surgeries to improve healing. in 1999 [ 1 ]. CIOS :: Clinics in Orthopedic Surgery ACL tears don't heal as such. Arthroscopic debridement of the mucoid degeneration of the ACL was safe and effective in the patient. The https:// ensures that you are connecting to the 2006;69(9):44952. Average postoperative International Knee Documentation Committee (IKDC) and Knee Injury and Osteoarthritis Outcome Scores (KOOS) were 71.2 (42.5 to 92.0) and 78.2 (26.4 to 99). Mucoid degeneration of ACL. MDACL is diagnosed by MRI, showing a celery stalk sign, and is confirmed by tissue biopsy and histological examination [7]. Later studies reported that changes consist of mucoid Results degeneration, neovascularisation, and tendon sheath hyper- Nineteen patients met the inclusion criteria and were inclu- trophy. Second, methodological quality assessment showed that three studies had low methodological quality. Lintz F, Pujol N, Boisrenoult P, Bargoin K, Beaufils P, Dejour D. Knee Surg Sports Traumatol Arthrosc. The aetiology of MDACL is not clearly understood. Background: Mucoid degeneration of the anterior cruciate ligament (ACL) is an uncommon non-traumatic cause of knee pain and motion restriction, typically seen in a middle-aged population. Typically patients present with knee pain or restricted movement, although often other potential causes for the patient's symptoms are found. The patient presented with extension block of the knee. Arthroscopic treatment may include ACL resection, which raises the questions about the harmlessness of this procedure and the risk of anterior instability. Orthop Traumatol Surg Res. Mucoid degeneration is characterized by an increase in the mucoid ground substance in the connective tissue containing glycoprotein and mucoprotein [ 4 ]. Background: [Effectiveness of bone-anterior cruciate ligament-bone allograft in reconstruction of anterior cruciate ligament under arthroscope]. It is a chronic degenerative change of a bulky ACL that may lead to notch . The retrospective study by Kim et al. Average improvement in flexion was 21.5 degrees (0 to 60 degrees). (Table 3). MeSH The purpose of this study was to investigate the outcome of management of MDACL by performing a systematic review of methods of treatment that have been reported. The main MRI finding of ACL mucoid degeneration is a celery stalk appearance [26, 27]. https://doi.org/10.1007/s00167-011-1433-0, Article National Library of Medicine 1999;81(2):304305. 2020 Jun 2. el Kadi KI, Marcaillou F, Blanc S, Salloum B, Dimontagliari C, Boutayeb F. Mucoid degeneration of the anterior cruciate ligament: a case report. 2011 Mar;25(3):262-5. Quality was assessed using the Methodological Index for Non-Randomized Studies (MINORS) criteria. Mucoid degeneration of the anterior cruciate ligament (ACL) is a rare cause of anterior knee pain (AKP). 2013 Oct;99(6):693-7. doi: 10.1016/j.otsr.2013.04.010. Seventeen females (67%) and eight males (33%) were included in the final analysis. Mucoid degeneration of the anterior cruciate ligament (ACL) is a very rare cause of knee pain. Methodological quality of the studies was assessed using the Methodological Index for Non-Randomized Studies (MINORS) criteria [11] (Table1). Mucoid degeneration, is the irreversible degeneration of the tissue with the infiltration of mucin(glycosaminoglycans) within the fibers[1][2]. An official website of the United States government. 2007;245 (3): 916-7. Arthroscopic debridement of the ACL results in satisfactory pain relief and improvement in knee outcome scores. Check for errors and try again. Cookies policy. MDACL is not uncommon, however, it is rarely symptomatic [4, 5]. If you believe that this Physiopedia article is the primary source for the information you are refering to, you can use the button below to access a related citation statement. JCM | Free Full-Text | Clinical Outcomes of Arthroscopic - MDPI Items are scored as 0 (not reported), 1 (reported but inadequate) or 2 (reported and adequate). 2010 Jun;96(4):400-6. doi: 10.1016/j.otsr.2010.02.008. Clipboard, Search History, and several other advanced features are temporarily unavailable. Unable to process the form. Bookshelf Le signe de la branche de cleri - ResearchGate We herein describe a case of PCL mucoid degeneration presented with secondary ACL . Mucoid degeneration of the anterior cruciate ligament. 2008 Jun;24(6):642-9. doi: 10.1016/j.arthro.2008.02.004. 2022 Mar;50(3):3000605221084865. doi: 10.1177/03000605221084865. An official website of the United States government. Roberts CC, Towers JD, Spangehl MJ et-al. Lintz F, Pujol N, Dejour D, Boisrenoult P, Beaufils P. Anterior cruciate ligament mucoid degeneration: selecting the best treatment option. Several authors have identified this condition, described their experiences, and suggested their own guidelines for management. 1173185. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. Federal government websites often end in .gov or .mil. The primary intervention was arthroscopic ACL debridement in eight studies; this was combined with notchplasty in cases of impingement with the lateral wall of the notch in five studies [6, 14, 16,17,18] (Table 3). The presence of intraligamentous mucoid degeneration in the ACL is demonstrated as a source of knee pain without instability and partial ACL debridement did not preclude adequate knee stability. Anterior cruciate ligament reconstruction was required in only one young patient due to disabling instability. and transmitted securely. J Chin Med Assoc. https://doi.org/10.1007/s002560100336, Narvekar A, Gajjar S (2004) Mucoid degeneration of the anterior cruciate ligament. The anterior cruciate ligament (ACL) is an important ligament in the knee. Case report: intra-tendinous ganglion of the anterior cruciate ligament Resnick D, Kransdorf MJ. Ahuja A, Parekh C, Salomon A, Lawande M, Daftary A. Skeletal Radiol. Reeducation. Mucoid degeneration,: like degenerative arthritis of a joint, generally occurs as a results of aging. [18] did not comment on an association between MDACL and chondral or meniscal lesions: after the exclusion of that report, the total number of patients with associated chondral lesions was 226 out of 275 patients (82%) and 190 patients had meniscal lesions (69%). -, McIntyre J, Moelleken S, Tirman P. Mucoid degeneration of the anterior cruciate ligament mistaken for ligamentous tears. Keywords: The purpose of this study was to investigate the outcomes of management of mucoid degeneration of the anterior cruciate ligament (MDACL) by performing a systematic review of methods of treatment that have been reported. It often presents with progressive knee pain, restriction in range of motion without a significant history of trauma, and without knee instability. Anatomically, it is arranged in a crossed pattern with the Posterior Cruciate Ligament, forming an 'X', therefore, it is also known as cruciform ligament. This site needs JavaScript to work properly. https://doi.org/10.1016/j.jclinepi.2009.06.005. Epub 2018 Aug 22. sharing sensitive information, make sure youre on a federal Anterior Cruciate Ligament (ACL) Mucoid Degeneration Anatomy Anterior Cruciate Ligament, is an important structure of the knee joint. Arthroscopy 24(6):642649. Generally, we know little about this condition. Two reviewers independently screened the titles and abstracts of the retrieved records for eligibility. Arthroscopic resection of ACL mucoid degeneration is effective for treating pain and flexion limitation, but at the expense of anterior laxity. In this review, the mean age of patients ranged from 31 to 78years; mean age was highest in the study of Kim et al. -, Makino A, Pascual-Garrido C, Rolon A, Isola M, Muscolo DL. There was an improvement in postoperative range of motion and outcome scores (Lysholm and International Knee Documentation Committee scores and the Knee Injury and Osteoarthritis Outcome Score). Mucoid degeneration (MD) of the anterior cruciate ligament (ACL) is a well-recognized pathology characterized by the degradation of collagen fibers and infiltration of a mucoidlike substance, [1,2 . 2022 Nov 24. doi: 10.1007/s00402-022-04659-z. Mucoid degenerated anterior cruciate ligament (ACL) managed by arthroscopic ACL reconstruction: A case series. Partial Anterior Cruciate Ligament - ACL - Tears - Howard J. Luks, MD Clin Orthop Surg 10(3):307314. 8600 Rockville Pike Knee Surg & Relat Res 33, 26 (2021). Download Citation | On Feb 1, 2023, O.R. Role of ultrasound-guided decompression in management of mucoid degeneration of the anterior cruciate ligament. Diffuse Intrasubstance Signal Abnormalities Ofthe Posterior Cruciate The lesion may manifest as an elongated cyst along the long axis of the ACL, or as an enlarged ACL. 1). Postoperative ACL laxity is a common finding after ACL arthroscopic debridement, however, symptomatic instability is not. Clipboard, Search History, and several other advanced features are temporarily unavailable. The reported restriction of range of movement was flexion deficit in four studies [3, 13, 15, 17], extension deficit in one study [14] and combined flexion and extension deficit in four studies [6, 16, 18, 19] (Table4). 5. Arthroscopic findings. We report a case of mucoid degeneration of the anterior cruciate ligament (ACL). 1. The mean follow up ranged from 13 to 72months. 8600 Rockville Pike Kim TH, Lee DH, Lee SH, Kim JM, Kim CW, Bin SI. Introduction: Mucoid degeneration of the anterior cruciate ligament (ACL) is a little-known entity. Epub 2011 Feb 18. The .gov means its official. proposed a different intervention called reduction plasty, whereby the hypertrophic ACL is reduced to normal size without excision of all mucoid substance [17]. MDACL is differentiated from synovial cysts of the anterior cruciate ligament (ACL) where, in MDACL, mucoid tissue intermingles within ACL fibres and is not contained within a cyst [3]. Mucoid degeneration of the anterior cruciate ligament: Management and outcome.. Clin Orthop Surg. The need for simultaneous or delayed ACL reconstruction should be discussed with patients in case total resection of the ACL is to be performed, particularly in young active patients. Arthroscopic management of mucoid degeneration of anterior cruciate ligament. Epub 2010 May 8. . Hide glossary Glossary. Case report: Sep 2017 - Feb 20186 months. Part of 2022 Nov 24. doi: 10.1007/s00402-022-04659-z. Chudasama et al. Epub 2011 Feb 18. The need for delayed ACL reconstruction should be discussed preoperatively, especially if complete resection of the ACL is to be performed. Knee Surg Sports Traumatol Arthrosc. Mucoid change or mucoid degeneration refers to the irreversible tissue degeneration due to the accumulation of mucin within the fibers of tendons, ligaments, and fibrocartilage. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). 2009. AJR Am J Roentgenol. However, symptomatic instability was not common. AJR Am J Roentgenol. CAS Bethesda, MD 20894, Web Policies Online ahead of print. This site needs JavaScript to work properly. It results in postoperative laxity, but rarely in frank instability. The inclusion criteria for this study were (1) studies including symptomatic patients with mucoid degeneration of the ACL, (2) studies of 10 or more patients, (3) a minimum of 6months follow up and (4) patients treated conservatively or surgically (arthroscopic debridement with or without simultaneous ACL reconstruction). 2022 Mar;14(1):76-89. doi: 10.4055/cios20163. Hamdaoui and others published Le signe de la branche de cleri | Find, read and cite all the research you need on ResearchGate -, Fealy S, Kenter K, Dines JS, Warren RF. . Study record managers: refer to the Data Element Definitions if submitting registration or results information.. Search for terms The mean MINORS score was 9.5 out of 16 (412). 2018 Jun;25(3):445-452. doi: 10.1016/j.knee.2018.02.012. Pre-debridement arthroscopic view showing yellowish content in the anterior cruciate ligament. Anterior cruciate ligament ganglia and mucoid degeneration: coexistence and clinical correlation. have described the following MRI criteria [4]: (1) high signal intensity in the T1 and T2 sequences, (2) increased ACL volume and (3) continuous fibres of ACL shown in the T2 sequence. Four studies reported only postoperative scores, which were comparable to those in other studies. Before Arthroscopic management of mucoid degeneration of anterior cru Mucoid degeneration of the anterior cruciate ligament - PubMed These appearances must be differentiated from mucoid degeneration of the intact ACL. A systematic literature search in the databases MEDLINE, Embase, Google Scholar, Cochrane, ISI web of science and Scopus was performed through July 2020 by three independent reviewers. Introduction to Arthroscopic Debridement official website and that any information you provide is encrypted For non-comparative studies, this consists of eight questions. Mucoid degeneration of ACL Justamom21 Feb 17, 2023 7:27 AM Among other conditions - osteoarthritis, osteopenia, spondylolisthesis- an MRI report showed "severe mucoid degeneration of the ACL" in my left knee. The mean age of patients ranged from 31 to 78years. First, our literature search revealed a heterogeneous group of studies dominated by case reports and case series, with no randomised controlled trials. Arthroscopy. Arthroscopic findings. 2013 Jun 20;15:59. doi: 10.11604/pamj.2013.15.59.2534. MAUDE Adverse Event Report: GENZYME BIOSURGERY (RIDGEFIELD) SYNVISC ONE Outcome of Arthroscopic Treatment of Mucoid Degeneration of the Anterior Cruciate Ligament. just over two decades ago [], the interest in this condition has quickly gathered pace in the orthopaedic community.Little is known about this condition that affects 1.8-5.3% of the population as per magnetic resonance imaging (MRI) diagnosis [2, 3]. Bookshelf Careers. All studies focused on the outcome of arthroscopic debridement of MDACL, with no studies on conservative treatment. Am J Roentgenol 182(5):12831287. Sasaki R, Nagashima M, Takeshima K, Otani T, Okada Y, Aida S, Ishii K. J Int Med Res. JBR-BTR. (A) Bulging of, Fig. Arthroscopic treatment of mucoid degeneration of the anterior cruciate Clinical significance of T2*-weighted gradient-echo MRI to monitor Postoperative follow-up included standard radiography and dynamic examination, measuring laxity with a Telos device. Management of mucoid degeneration of the anterior cruciate ligament: a systematic review, https://doi.org/10.1186/s43019-021-00110-6, https://doi.org/10.1302/0301-620X.81B2.0810304, https://doi.org/10.1007/s00167-011-1433-0, https://doi.org/10.2214/ajr.182.5.1821283, https://doi.org/10.1007/s00167-012-1991-9, https://doi.org/10.1016/j.arthro.2003.11.030, https://doi.org/10.1016/j.jclinepi.2009.06.005, http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42018087782, https://doi.org/10.1046/j.1445-2197.2003.02748.x, http://journals.sagepub.com/doi/10.1177/2325967118786930, http://www.ijcrar.com/abstractview.php?ID=228&vol=4-11-2016&SNo=3, https://doi.org/10.1016/j.arthro.2008.02.004, https://doi.org/10.1016/j.jajs.2015.12.001, https://doi.org/10.4055/cios.2018.10.3.307, http://creativecommons.org/licenses/by/4.0/, http://creativecommons.org/publicdomain/zero/1.0/. Mucoid degeneration of the anterior cruciate ligament (ACL) of the knee can cause knee pain and other symptoms. FOIA It is a chronic degenerative change of a bulky ACL that may lead to notch impingement syndrome in the absence of instability symptoms and significant trauma history [ 1, 2, 3, 4 ]. Data extracted included mean age and gender of the patients, duration of follow up, associated chondral and meniscal lesions, interventions and outcomes. Anterior cruciate ligament mucoid degeneration: Selecting the best All nine studies assessed the outcome of arthroscopic debridement of MDACL. Disclaimer. Postoperative ACL laxity is common after arthroscopic ACL debridement, however, symptomatic instability is not. statement and At the time the article was last revised Dai Roberts had no recorded disclosures. Anterior cruciate ligament mucoid degeneration: a review of the literature and management guidelines. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. Orthopaedics & Traumatology: Surgery & Research. Assessment of Anterior Cruciate Ligament (ACL) Degeneratio Mucosa Treatment Its function is to stabilize the knee while bending and rotating; the ACL also keeps the knee from shifting out of place or moving anteriorly (toward the front) with pivoting activities. Arthroscopy 20(2):141146. On clinical examination, the active range of motion showed a flexion deficit. Google Scholar, Lintz F, Pujol N, Dejour D, Boisrenoult P, Beaufils P (2010) Anterior cruciate ligament mucoid degeneration: selecting the best treatment option. Mucoid degeneration of the anterior cruciate ligament. Arthroscopic examination analyzed the ACL aspect and its associated lesions (meniscus, cartilage). Anatomically, it is arranged in a crossed pattern with the Posterior Cruciate Ligament, forming an 'X', therefore, it is also known as cruciform ligament. ACL mucoid degeneration is an uncommon pathological condition; the pathogenesis, prevalence, and . Online ahead of print. Besides, the patient may also have trouble in moving. Federal government websites often end in .gov or .mil. 2022 Mar;50(3):3000605221084865. doi: 10.1177/03000605221084865. Only three studies mentioned failed conservative treatment as an inclusion criterion [14, 15, 18]. Mucoid degeneration (MD) of the anterior cruciate ligament (ACL) is a rare pathological entity with disputed theories of origin. Privacy Other theories include Degenerative theory- MD could occur due to ageing.[3]. Mumbai, Maharashtra, India. Bergin D, Morrison WB, Carrino JA et-al. Average patient age was 49 (22 to 68) years. Clipboard, Search History, and several other advanced features are temporarily unavailable. Mucoid degeneration of the anterior cruciate ligament (MD-ACL) was first characterized by Kumar et al. Eight studies showed postoperative improvement in range of motion, whereas Khanna et al. Most authors believe that partial ACL resection is the treatment of choice in symptomatic MD of the ACL. Anterior cruciate ligament mucoid degeneration: a review of the literature and management guidelines. Magn Reson Imaging Clin N Am. Mucoid degeneration of the ACL is suspected when an apparently thickened and ill-defined ligament with increased signal intensity on all sequences in MRI is identified in a patient with physically intact ligament and no obvious trauma history. Knee Surgery, Sports Traumatology, Arthroscopy. Unauthorized use of these marks is strictly prohibited. https://doi.org/10.1007/s00167-012-1991-9, McIntyre J, Moelleken S, Tirman P (2001) Mucoid degeneration of the anterior cruciate ligament mistaken for ligamentous tears. In these studies, the total number of patients with a postoperative positive Lachman test was 40% (77 of 194 patients). Knee Surg Sports Traumatol Arthrosc 21(3):658663. Epub 2021 Mar 8. Epub 2018 Jan 2. Coronal T2 weighted fat suppressed fast spin echo image showed complex anterior cruciate ligament ganglion cyst arising from superior aspect of ligament. 2. Rajani AM, Shah UA, Mittal ARS, Gupta S, Garg R, Punamiya M. Knee Surg Relat Res. PMC Conclusions Our study provides further evidence that arthroscopic total or partial excision of anterior cruciate ligament is a safe and effective treatment for mucoid degeneration of the anterior . ADVERTISEMENT: Supporters see fewer/no ads. MUCOID DEGENERATION OF ACL - ARTHROSCOPIC TREATMENT 2,375 views Sep 15, 2019 23 Dislike Dr. Prateek Joshi- Ortho 1.02K subscribers Notice Age-restricted video (based on Community Guidelines). Risk factors Predisposing factors include the following 1: aging Mucoid degeneration itself is described as a yellow or brown substance which can be either seen through the most anterior fibers of the ACL or found by probing between them [ 19, 35] (Fig. Bergin et al. Loganathan D, Soma Sundar S, Sundar S, Sahanand S, Rajan DV.
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