You may need to have a dental exam before you begin treatment with Prolia. Continue reading, Yes, Prolia does appear to weaken your immune system. Tell them if you have any scheduled dental work coming up. They can treat the infection as needed. Use of the terms female and male in this article refers to sex assigned at birth. 1 shot every 6 months could mean fewer doses. * Sex and gender exist on spectrums. More common side effects in females* who received Prolia for osteoporosis after menopause included: More common side effects in males* who received Prolia for osteoporosis included: More common side effects in people who received Prolia for osteoporosis due to drugs called glucocorticoids included: More common side effects in people who received Prolia to stop bone thinning due to certain cancer treatments included: For a complete list of all the side effects reported with Prolia, see the drugs prescribing information. Vertigo (dizziness) was reported in some people who received Prolia for osteoporosis, but this was a less common side effect. If your pain doesnt ease with OTC options, your doctor may suggest prescription pain medication. You may need to stop using the medicine for a short time. Over time, Prolia can reduce bone loss and make your bones stronger. Tell your doctor about all other medicines you use. With low BMD your bone tissues have less mineral, which means they become weaker. But certain choices and habits accelerate the process.
Denosumab (Prolia) for postmenopausal osteoporosis Talk to your health care professional or pharmacist for more information. If your doctor says this is safe for you, youll be shown how to inject the medication. Stopping some drugs leads to withdrawal symptoms because your body is used to the drug and needs it for you to feel normal. We comply with the HONcode standard for trustworthy health information. These side effects include: Your risk for these serious side effects may be higher if youre older and have certain dental procedures. This is the drugs mechanism of action. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. These side effects may include: Its not known what percentage of people in clinical trials developed dental or jaw-related side effects. To learn how Prolia and Tymlos are alike and different, see this comparison. If you miss a dose of Prolia, you should receive your injection as soon as you can. In addition to treating osteoporosis, which is described just above, Prolia also has other uses. Whats the Connection Between Estrogen and Osteoporosis? WebTake calcium and vitamin D as directed by your doctor, usually 1000 milligrams of Not getting enough calcium in your diet can lead to fragile, brittle bones that are more prone to fractures and disease. This could include having: Before taking Prolia, share your dental history with your doctor. If you want to stop taking Prolia, tell your doctor. For more information, you can refer to the drugs prescribing information. Some research has shown that alcohol consumption may increase your risk of osteoporosis, a bone fracture or impaired healing after a fracture. Continue reading, Prolia (denosumab) has not been associated with weight gain in clinical studies. Now i am worried that i've been taking K2 which also takes calcium from the blood to the bones. Last updated on Feb 8, 2023. Your doctor may also have you take certain supplements that contain calcium and vitamin D while youre receiving Prolia. You should not breastfeed while using this medicine. This drug may decrease your body's ability to fight infection. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). For more information about the uses of Prolia, see the Is Prolia used for osteoporosis? and Is Prolia used for other conditions? sections below. Sciatica is described as a shooting pain that travels from the lower back down a leg.
Prolia side effects: What you should know - Medical Let your doctor know if you have questions about which drug is recommended for you. BMD was increased by 8.8% at the lumbar spine, 6.4% at the total hip, and 5.2% at the femoral neck in trials that measured BMD after three years of treatment with Prolia. Denosumab is contraindicated in women with hypocalcaemia. Please see Prolia full Motion sickness, nausea, and vomiting can occur as a part of vertigo. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Do not use denosumab if you are pregnant. Be sure to read this information carefully each time. With bone loss, your body loses old bone tissue faster than it makes new bone tissue. If you have serious side effects from Prolia, call your doctor right away. Prolia contains the active drug denosumab, while Fosamax contains the active drug alendronate. for breast cancer that has not spread to other parts of the body. If your pain becomes severe, your doctor may recommend other treatment options to replace Prolia. If youre concerned about tingling while using Prolia, talk with your doctor. But weight gain may be a symptom of a side effect called peripheral edema. If you develop hypocalcemia, your doctor will typically have you stop using Prolia. (A placebo is a treatment with no active drug.). This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. The most common medications prescribed to lower cholesterol are statins. With arthritis, you have pain and inflammation of your joints. Get useful, helpful and relevant health + wellness information, 9500 Euclid Avenue, Cleveland, Ohio 44195 |, Important Updates + Notice of Vendor Data Event, low levels of calcium or Vitamin D in the blood, an unusual reaction to denosumab, other medicines, foods, dyes, or preservatives, medicines that lower your chance of fighting infection, steroid medicines like prednisone or cortisone, allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue, signs and symptoms of infection like fever or chills; cough; sore throat; pain or trouble passing urine, signs of low calcium like fast heartbeat, muscle cramps or muscle pain; pain, tingling, numbness in the hands or feet; seizures. But unlike generics, which are made for nonbiologic drugs, biosimilars are made for biologic drugs.). Before your appointment, write down questions, such as: How will Prolia affect my body, mood, or lifestyle? After you stop taking Prolia, youre more likely to experience bone loss, and your risk of a vertebral fracture increases. Do not treat yourself. Find out what it means, how its calculated, and more. If youre able to become pregnant, your doctor will have you take a pregnancy test before you start Prolia treatment. While youre receiving Prolia treatment, your doctor will monitor your cholesterol levels with regular blood tests. You can learn more about how we ensure our content is accurate and current by reading our. Courtney Sullivan, Certified Yoga Instructor, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT. Now i'm wondering if i shouldn't take K2. Continue reading, Prolia (denosumab) does increase bone density. Check with your doctor if you have more questions about these drugs. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. If your Prolia treatment is stopped, talk to your doctor about other medicine that Doctors sometimes prescribe Prolia to treat osteoporosis and bone thinning. Protect from light and do not freeze. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Prolia is also used to treat glucocorticoid-induced osteoporosis in men and women at high risk of bone fracture. Its given to adults who are at high risk for bone fractures.
Prolia - Patient Information Leaflet (PIL) - (emc) - medicines Certain kidney problems, such as chronic kidney failure, can cause a low calcium level in your blood. Examples of conditions Prolia is used off-label to treat include: Prolia is one option available to treat osteoporosis and reduce bone loss in people with a high risk for bone fracture. For example, in the studies, people taking Prolia for up to 8 years didnt have significant side effects compared with people taking a placebo.
Osteoporosis Medications (Bisphosphonates) - Johns Hopkins Get emergency medical help if you have signs of an allergic reaction to Prolia: hives, itching, rash; difficult breathing, feeling light-headed; swelling of your face, lips, tongue, or throat. Follow your doctor's instructions about any restrictions on food, beverages, or activity. They can also tell you about other treatment options available for osteoporosis and bone loss prevention. If youd like more information about Prolia use during pregnancy or while breastfeeding, talk with your doctor. They can suggest ways to help relieve these side effects. Hair loss with Prolia was reported after the drugs initial studies were done and it was approved for use. They may recommend ways to ease your symptoms and determine whether you should keep taking Prolia. All rights reserved. Both are prescription medicines.
Prolia 2023 Healthline Media UK Ltd, Brighton, UK. But nausea may be a symptom of side effects such as vertigo or constipation. Most Medicare plans and other insurance plans cover Prolia. Use effective birth control while using denosumab and for at least 5 months after your last dose. Tell your doctor right away if you become pregnant while taking Prolia. have low blood calcium; or are pregnant or plan to become pregnant, as Prolia may harm your unborn baby; or are allergic to denosumab or any ingredients in Prolia. Be sure to talk with your doctor about which medication is right for you. You may be interested in learning how Prolia compares to the medication Fosamax. If you have low blood calcium, it may get worse during treatment.
Prolia (Injection) Uses, Dosage & Side Effects - Drugs.com If youre able to become pregnant, your doctor will order a pregnancy test for you before you take Prolia. Nausea can sometimes be a symptom of severe constipation. Its not known if Prolia is safe or effective for use in children. Policy. For this reason, some calcium supplements are combined with vitamin D. This vitamin is available in two forms, vitamin D 2 (ergocalciferol) and vitamin It is often used in osteoporosis.
Take good care of your teeth and gums while you receive Prolia. It works with your immune system to help prevent bone loss. Women should inform their doctor if they wish to become pregnant or think they might be pregnant.
supplements Use of the term male in this article refers to sex assigned at birth. If youve noticed hair loss since starting Prolia treatment, talk with your doctor. Our phase IV clinical studies alone cannot establish cause-effect relationship. Ask your plan if they cover the drug, and what the cost will be for you. Youll receive Prolia from a healthcare professional as an injection under the skin in one of the following areas: Prolia contains the active drug denosumab, which is a biologic medication.
Osteopenia Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products.
Denosumab Injection: MedlinePlus Drug Information Take only the amount of calcium and vitamin D that your doctor has prescribed. Learn how to increase or maintain bone density here. Brush and floss your teeth regularly. Prolia pregnancy and breastfeeding warnings. This is because your body doesnt make enough bone, or it loses bone faster than it makes new bone. Prolia is a prescription medicine used to treat osteoporosis in men and women who will be taking corticosteroid medicines Xgeva is also used to treat giant cell tumor of the bone. Side effects that you should report to your doctor or health care professional as soon as possible: Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome): This list may not describe all possible side effects. These lists dont include all possible side effects. 8,432 people who take Prolia and Calcium together, and have interactions are studied. But if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist. With osteopenia, your bone mineral density (BMD) is lower than usual. Call your doctor for medical advice about side effects. For Xgeva, talk to your pediatrician regarding the use of this medicine in children. This increases your risk for bone fractures. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Its a prescription drug thats used to treat osteoporosis and other forms of bone loss. Different individuals may respond to medication in different ways. You should talk with your doctor if you develop any mild side effects that concern you. If youd like to know more about the differences and similarities of Prolia and Evenity, see this comparison. The lists below describe some of the more common side effects that Prolia may cause. Certain side effects of Prolia that may last longer than others include: Ask your doctor about serious or long-lasting side effects of Prolia and what you should know before starting this drug.
You Serious infections may occur during treatment with Prolia. So your healthcare provider will likely ask you to take calcium and vitamin D supplements if youre not taking them already. Yes, if recommended by your doctor, you can stop taking Prolia. Do not stop using this medicine without first talking to your doctor. WebMost people can get adequate calcium through their diet if they make an effort. Women Prolia may lower the level of calcium in your blood. They may also suggest exercises to help improve your bone strength and lower your risk for fractures and osteoporosis. WebStudies have shown that people who live more sedentary lifestyles are at an increased risk of developing osteoporosis. Youll receive 60 mg/mL of Prolia once every 6 months. Xgeva is another brand of denosumab used to prevent bone fractures and other skeletal conditions in people with tumors that have spread to the bone. Since different people No, weight gain wasnt reported as a side effect of Prolia in clinical trials. You should not receive Prolia if you are allergic to denosumab, or if you have: low levels of calcium in your blood (hypocalcemia); or; if you are pregnant. Heres a short list of some of the mild side effects that Prolia can cause. They can help answer any questions you have about side effects from taking the drug. Some side effects of Prolia may go away on their own within a few days or weeks after starting treatment. Here are a few questions to consider asking your doctor: You can also learn more about osteoporosis treatment options here. Also describe any vitamins, herbs, or supplements you use. This was one of the most common side effects in clinical trials of females who received Prolia for osteoporosis after menopause. Some people who take Prolia develop severe bone, joint, or muscle pain. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. (To learn more, see the Precautions for Prolia section below.).
But if you think youre having a medical emergency, call 911 or your local emergency number. Talk with your doctor if youd like to know about taking generic denosumab.
Prolia: Side Effects, Alternatives, How It's Administered, Lifestyle changes that can help improve cholesterol levels include exercising regularly and eating a healthy diet. Also, hair loss may be related to other medications you take or health conditions you have. If you drink alcohol, talk with your doctor about how much is safe to drink with your condition. You should also talk with your doctor if you have nausea during treatment. eHealthMe is studying from 138,307 Prolia users for its effectiveness, alternative drugs and more. The two most common forms of arthritis are osteoarthritis and rheumatoid arthritis (RA).
MEDICATION GUIDE Prolia (PR-lee-a) (denosumab) Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. But its believed that these side effects are rare.